What is an embryo?

An embryo is the early stage of the development of a multicellular organism.  Embryonic development is the part of the life cycle that starts evolving simply after fertilization and maintains through the formation of frame structures, inclusive of tissues and organs.

What is Embryo Freezing or Cryopreservation?

Embryo Freezing is another technique used in cryopreservation that also helps in preserving and ascertaining future fertility chances. Usually, people who choose embryo freezing procedures are undergoing cancer treatment, hormone therapy, or another medical intervention that hampers and affects their fertility.

For a better understanding of cryopreservation, visit our blog on our official website and read all about it. 

History of Embryo Freezing

The first successful pregnancy because of freezing a healthy embryo was executed in the 1980s. Since then, many humans have frozen embryos and used them later. The procedure starts with a trusted Source the usage of hormones and other medications to stimulate the production of potentially fertile eggs. A health practitioner then extracts the eggs from the ovaries, both for fertilizing in a lab or for freezing.

Anyone can store an embryo if they hope to come to be pregnant within the future, to donate to others, for scientific studies, or for education purposes. Fertilization often results in a couple of embryos, and the health practitioner can freeze and maintain the last embryos.

Why does one freeze embryos?

Embryo freezing regularly takes place after people have treatments to attempt to get pregnant. Examples include in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).

These strategies fertilize eggs with sperm, and from time to time create more embryos. For a better understanding of the steps taken in freezing embryos, visit our blog on our official website and read all about it. 

You may also choose to freeze more embryos and use them later if:

  • Postpone or cancel implantation into your uterus after an egg is already fertilized.
  • Want to postpone IVF to a later date.
  • Want an option in the case early attempts at fertility remedy fail.
  • Choose to donate unused embryos to other people seeking to get pregnant or to researchers as opposed to ruin them.

Embryo freezing is also used for fertility renovation. For example, a transgender guy (transitioning to male) also may freeze eggs or embryos earlier than taking hormones for the transition or having gender affirmation surgery. Or a woman at delivery (DFAB) with cancer might need to store fertilized eggs earlier than beginning chemotherapy or radiation therapy if that treatment ought to affect their capacity to get pregnant. 

How does one freeze embryos?

The main intention of freezing embryos is to maintain them for later use. The largest challenge is the water within the cells. When this water freezes, crystals can shape and burst the cellular. For this very reason, the Cryopreservation technique was used and there are two distinctive ways for freezing embryos which include, 

  • Slow freezing
  • Vitrification

Cryopreservation: To save this from going on, the health practitioner makes use of a procedure known as cryopreservation. It entails replacing the water in the cellular with a substance called a cryoprotectant. The medical doctor then leaves the embryos to incubate in growing ranges of cryoprotectant before freezing them. After eliminating most of the water, the health practitioner cools the embryo to its upkeep country. They then use certainly one of the freezing techniques:

Slow freezing: This includes setting the embryos in sealed tubes, then slowly lowering their temperature. It prevents the embryo’s cells from aging and reduces the danger of harm. However, gradual freezing is time-eating, and it requires highly-priced equipment.

Vitrification: In this method, the physician freezes the cryoprotected embryos so speedy that the water molecules do now not have time to form ice crystals. This facilitates shielding the embryos and increases their charge of survival for the duration of thawing.

After the system of freezing is whole, the medical doctor shops the embryos in liquid nitrogen.

Various steps during the process?

Step 1: Ovarian Stimulation 

IVF process is to stimulate the production of 10-15 eggs, to help the female partner and increase the chances of conceiving and getting pregnant.

Step 2: Egg and sperm collection:

Once the eggs are retrieved fertilization process begins, where the mature eggs are placed in an incubator and are fertilized with sperm within a couple of hours. 

Step 3: Fertilisation

Fertilization involves the observation of embryos until it reaches the blastocyst stage. Once the sperm fertilizes the egg, it becomes an embryo. Monitoring of the embryo is completed in 2 to 6 days. 

Step 4: Embryo development

After the embryo develops into the blastocyst stage which generally takes place within 2 to 6 days of the fertilization process. 

Step 5: Preserving of embryos:

Lastly, these developed embryos are then stored and preserved in our labs enabled with advanced technology. 

For a better understanding of the above steps, visit our official website at ZiviaIVF and read all about embryo freezing. 

Embryo freezing is beneficial?

Embryo freezing may be a higher choice for the following people

  • People with genetic disorders 
  • A person who will soon go through chemotherapy
  • All those who take medicinal drugs that have an effect on fertility
  • Same-gender couples and LGBTQ+ population who desire to have children in future

Are there any side effects?

Usually, there are no severe side effects but there are some and they include

  • bleeding
  • bloating
  • cramping 
  • vaginal discharge
  • contamination
  • overstimulation of the ovaries


Hope this blog was helpful and cleared all your doubts regarding embryo freezing. For more such articles on IVF and its treatment visit our official website at ZiviaIVF

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